The composition of the gut microbiota is associated with various disease states, most notably inflammatory bowel disease, obesity and malnutrition. This underlines that analysis of intestinal microbiota is potentially an interesting target for clinical diagnostics. Currently, the most commonly used sample types are feces and mucosal biopsy specimens. Because sampling method, storage and processing of samples impact microbiota analysis, each sample type has its own limitations.
[Anal and perianal mycoses. Anal fungal flora in infant and adult (author's transl)].
Sexual Behavior and Substance Use Can Affect Gut Microbiome
Get the content you want anytime you want. HIV is one of many diseases that can influence the composition of the intestinal microbiome. However, gut flora can vary significantly from person to person depending on certain behaviors. To explore how sex practices and substance use can alter the organisms in the intestines, a team of researchers at UCLA and Cedars-Sinai Medical Center in Los Angeles studied archived specimens and clinical data on a group of 37 relatively young HIV-positive men who have sex with men. The subjects, who were part of a larger study on drug abuse that took place from to , had given rectal sponge specimens, blood and urine samples, and answers to detailed questions about sexual practices and drug use at roughly 6-month intervals for the duration of the study. The samples yielded DNA, which was then sequenced to provide profiles of individual microbiomes.
Corresponding author: A Boutall boutall icloud. This typically presents with pain on defecation and blood spotting on toilet paper. These symptoms are due to an ischaemic mucosal ulcer within a high-pressure sphincter. The fissure is usually visible at inspection of the gently distracted anus Fig.
Rectal culture is a lab test to identify bacteria and other germs in the rectum that can cause gastrointestinal symptoms and disease. A smear of the swab is placed in culture media to encourage the growth of bacteria and other organisms. The culture is watched for growth. The organisms can be identified when growth is seen. More tests may be done to determine the best treatment.